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Nanocs/Innovative Life Science Products and Services/100 mg/PG2-DSML-20k
Synonym: Maleimide PEG DSPE, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine PEG Maleimide, DSPE-PEG-Mal.
Description:
DSPE PEG Maleimideis one of Nanocs reactivephospholipid PEG reagents that can react with sulfhydryl (thiol, -SH) groups.DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine)is a saturated 18C phospholipid that is highly hydrophobic. PEG linker (polyethylene glycol), on the other hand, offers good hydrophilicity and water solubility.MaleimidefunctionalDSPE PEGhas excellent reactivity towards sulfhydryl/thiol groups derived from various molecules. Reaction betweenmaleimideandthiolproceeds easily at neutral pH.Maleimide PEG DSPEis one of most commonly used reactive phospholipids to conjugate antibodies, peptides or other ligands to the surface of liposome and otherlipid PEGnanoparticles. Pegylated phospholipids have longer blood circulation time and higher stability for encapsulated drugs. Nanocs has developed a comprehensive collection of thiol reactivemaleimide phospholipid PEGproducts that have high purity, various molecular weights and excellent chemical reactivity. These lipid PEG conjugates demonstrate excellent amphilphilic properties and offer superior advantages for small and large molecule drug formulation and delivery.
Physical Properties:
- Form: Solid powder;
- Color: White;
- Solubility: Soluble in chloroform and warm water;
- Reactive group: Maleimide;
- Reactive to: Sulfhydryl (-SH);
- Lipid type: 18C PE, saturated;
- Purity: >95%
Storage Conditions:
- Store at -200C. Avoid frequent thaw and freeze.